Aklief 50 Micrograms / G Cream 75Gm BottleAKLIEF Cream is an innovative topical single agent retinoid cream proven safe and effective for acne on your face, shoulders, chest, and back. 1 3 AKLIEF Cream contains the retinoid molecule trifarotene, which helps the skin replace its old skin cells at a faster speed, exfoliating away the old cells in the process and helps prevent new acne from forming. 1 It may also reduce inflammatory acne often experienced with pimples.