Pro-AdaptBioMatrix separates its progesterone and estriol products, allowing for precision dosing and optimal results. BioMatrix progesterone is derived from an extraction of the steroidal backbone of the Mexican Wild Yam (Dioscorea villosa). It is bioidentical, which means it possesses the same molecular structure as that produced naturally by the body. Vitamin E (mixed with tocopherols) is a blend of natural source alpha tocopherol and mixed tocopherols.