Cigarette smoke can reprogram cells in your airways, causing COPD to hang on after smoking ends Electronic cigarette use and its association with asthma, chronic obstructive pulmonary disease (COPD) and asthma COPD overlap syndrome among never cigarette smokers Broad range of studies show e cigs increase lung disease risk by 40 50% Stanton Glantz blog Frontiers Inhalation of nicotine containing electronic cigarette vapor exacerbates the features of COPD by inducing ferroptosis in ENaC overexpressing mice