What Is A Pod Vape System and How Does it Work? Electronic cigarettes (e cigarettes) are sometimes called e cigs, vapes, vape pens, and electronic nicotine delivery systems (ENDS). E cigarettes come in many shapes and sizes. Most e cigarettes contain nicotine. Get the facts about e cigarettes, Current evidence identifies health risks of e cigarette use; long term research needed American Heart Association Inside the Vaper's Den: E Cigarette Salvation and New Dangers