Does e cigarette use increase the risk of cancer? E cigarettes are likely to cause cancer, including in the lungs and mouth, according to a sweeping review of scientific evidence that challenges their positioning as a safer alternative to smoking. There is E cigarette vapor linked to cancer in mice National Institutes of Health (NIH) A scientific review has raised fresh concerns about the long term cancer risks of vaping, concluding that e cigarettes are probably carcinogenic, while also acknowledging significant gaps in the evidence. The analysis of reviews