Antony and CleopatraAntony and Cleopatra is a tragedy by William Shakespeare, believed to have been written sometime between 1603 and 1607. READ BY SIR ANTHONY QUAYLE AND CAST Antony and Cleopatra is a tragedy by William Shakespeare, believed to have been written sometime between 1603 and 1607. It was first printed in the First Folio of 1623. The plot is based on Thomas North's translation of Plutarch's Life of Marcus Antonius and follows the relationship between