BIOFREEZE Cool the Pain Patches 5 Large PatchesBiofreeze Patch features targeted, mess free application that penetrates quickly for up to 8 hours of long lasting relief. The flexible design of the Patch stays in place during activity for superior performance and comfort while providing pain relief to body parts such as back, neck, shoulder, knee, wrist, and foot. Designed to provide fast acting, long lasting, and deep penetrating pain relief for sore muscles, backaches, sore joints, and arthritis.