Xofluza 40 mg Tablet 1’sA single dose prescription medicine for the treatment and prevention of influenza. Key Indications XOFLUZA is an FDA approved antiviral used for eligible patients 5 years of age and older. Used to treat the flu when symptoms have lasted no more than 48 hours in: Otherwise healthy individuals. Individuals at high risk of flu complications. Prevention: Used to help prevent the flu following contact with an infected person (post exposure prophylaxis).