Do Vapes Set Off Smoke Alarms? Royal Flush Vape UK VS 1000E Vape Detection Sensor for Schools & Businesses Can Smoke Detectors Detect Vape Looking for advanced vape detector that can provide protection in an emergency situation? Your guests aren't the only ones checking in. So are their vape pens. With over 13 million regular vapers in the U.S. alone, unauthorized vaping is a major operational risk for hotels.