How Much Nicotine Is in a Cigarette: Facts and Breakdown This statement is common, but it is not true! According to the manufacturer, a single JUUL pod contains as much nicotine as a pack of 20 regular cigarettes! Say no to vaping. 10 15 vape puffs are roughly equivalent to one cigarette. We want to encourage and support families to have open and engaging conversations with young people to How Many Puffs of Vape are Equal to a Cigarette? EDGE Vaping