An updated overview of e cigarette impact on human health Respiratory Research Springer Nature Link Great question! Here's a clear comparison of smoking vs. vaping, especially in the context of surgical and skin health (like facelift outcomes): Smoking (Tobacco) WORSE overall Key Harms: The Chemistry of Vaping ChemistryViews Toki Let's be real, what's the difference between vaping versus smoking cigarettes? We know that vaping contains no tobacco and far less chemicals than cigarettes but the keyword here is 'less'.